Back to: How to Read an Insert Training Course

Click “play” below for optional audio.

Haga clic en “reproducir” a continuación para obtener audio opcional.

Let’s start diving into each section of the manufacturer insert. Quick refresher: the CDC defines contraindications (con·​tra·​in·​di·​ca·​tions) as conditions in a recipient that increases the risk for a serious adverse reaction. Also, the CDC states a product should not be administered when a contraindication is present. Let’s look at an example.

According to the DTAP vaccine manufacturer, if you have had a previous reaction to any diphtheria toxoid, tetanus toxoid, or pertussis-containing vaccine, then you should not accept this product. Similarly, if you experienced encephalopathy (brain disease, damage, or malfunction) within 7 days of a previous pertussis-containing vaccine with no other identifiable cause, then the manufacturer states you should not accept this product. Same for infantile spasms, uncontrolled epilepsy, or progressive encephalopathy.

Let’s look at another example!

The above example from the manufacturer for Ozempic (indicated for patients with type 2 diabetes) states someone with history of MTC or MEN 2 is contraindicated for this product. As well as anyone with a known hypersensitivity to semaglutide (active ingredient) or any of the product components (which you can find in the “Description” section of the insert). Don’t worry, we’ll cover that section soon!

Additionally, manufacturers might list contraindications in a boxed warning (see Ozempic example below).

Pay special attention to boxed warnings. They are designed to be the most important information on the insert!