Pharmaceutical Name

Trade (marketing or proprietary) name: Lipitor®

Generic (nonproprietary or active ingredient) name: atorvastatin calcium tablets

Indication and Usage

Reason the product has been approved for sale on the market.

The FDA has approved this HMG-CoA reductase inhibitor as an adjunct therapy to diet.

Manufacturer Insert

Ingredients

atorvastatin calcium, calcium carbonate, USP; candelilla wax, FCC; croscarmellose sodium, NF; hydroxypropyl cellulose, NF; lactose monohydrate, NF; magnesium stearate, NF; microcrystalline cellulose, NF; Opadry White YS-1-7040 (hypromellose, polyethylene glycol, talc, titanium dioxide); polysorbate 80, NF; simethicone emulsion.

Manufacturer-Listed Adverse Reactions

Per the CDC, adverse reactions are an undesirable medical condition that has been demonstrated to be caused by a vaccine. Evidence for the causal relation is usually obtained through randomized clinical trials, controlled epidemiologic studies, isolation of the vaccine strain from the pathogenic site, or recurrence of the condition with repeated vaccination (i.e., rechallenge); synonyms include side effect and adverse effect.

Nasopharyngitis (swelling of the nasal passages and the back of the throat), Arthralgia (joint pain), Diarrhea, Pain in extremity, Urinary tract infection, Dyspepsia (indigestion), Nausea, Musculoskeletal pain, Muscle Spasms, Myalgia (muscle pain), Insomnia, Pharyngolaryngeal (throat) pain, Malaise (discomfort), Pyrexia (fever), Abdominal discomfort, Eructation (belching), Flatulence, Hepatitis (inflammation of the liver tissue), Cholestasis (reduction/cessation) in the flow of bile), Musculoskeletal pain, Muscle fatigue, Neck pain, Joint swelling, Anaphylaxis, Angioneurotic edema (swelling), Fatigue, Myositis (disease that involves inflammation of the muscles), Tendon rupture, Peripheral neuropathy, Pancreatitis, Rhabdomyolysis (damaged skeletal muscle breaks down rapidly) with acute renal failure secondary to myoglobinuria (cola-like urine), Myopathy (disease of the muscle in which the muscle fibers do not function properly), Fatal and non-fatal hepatic failure, Immune-mediated necrotizing myopathy (IMNM), Biochemical abnormalities of liver function/liver enzyme abnormalities, Transaminases (liver enzymes) increase, Liver function test abnormal, Blood alkaline phosphatase increase, Creatine phosphokinase increase, Hyperglycemia (excessive amount of glucose circulates in the blood plasma), Nightmare, Epistaxis (nosebleed), Urticaria (hives), Vision blurred, Tinnitus (ringing ears), White blood cells urine positive (sign of inflammation within the urinary tract infection), Cognitive impairment (e.g., memory loss, forgetfulness, amnesia, memory impairment, confusion), Bullous rashes (including erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis), Dizziness, Depression, Interstitial lung disease.

Analytical Deep Dive

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Alternatives

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